Engineering Clostridia For N-Butanol Production From Lignocellulosic Biomass And CO2 Award Number: DE-EE0007005 CX(s) Applied: A9, B3.6 Bioenergy Technologies Office Date: 07/16/2015 Location(s): OH Office(s): Golden Field Office
Office of NEPA Policy and Compliance
July 16, 2015
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Engineering Clostridia For N-Butanol Production From Lignocellulosic Biomass And CO2
Award Number: DE-EE0007005
CX(s) Applied: A9, B3.6
Bioenergy Technologies Office
Date: 07/16/2015
Location(s): OH
Office(s): Golden Field Office
The U.S. Department of Energy (DOE) is proposing to provide federal funding to Ohio State University to develop engineered Clostridia strains and fermentation processes that can directly utilize cellulose and fix Carbon Dioxide (CO2) for n-butanol production from lignocellulosic biomass.
The proposed project activities would include genetic engineering of Clostridia for n-butanol production from cellulose and CO2/H2; study of fermentation kinetics and optimization of processes; omic analysis of mutants in fermentation; and process design & cost analysis. Genetic engineering activities would take place at the dedicated biomolecular engineering labs at Ohio State University (OSU) in Columbus, Ohio. Fermentation kinetics studies and optimization of processes would be conducted at both the dedicated microbiology labs at OSU and Green Biologics (GB) research lab in Columbus, Ohio. Omic analysis would occur at the University of Alabama’s (UA) dedicated lab in Tuscaloosa, AL. Process design and cost analysis would be completed by GB at their offices in Columbus, OH. The facilities where the proposed project would occur have been previously used for work that is similar to the activities included in the proposed project; therefore, no new or modified permits would be required, and no construction of new facilities or physical modifications to existing facilities would occur as a result of the proposed project.