The U.S. Department of Energy announced agreements with 24 organizations interested in collaborating to advance the Genesis Mission, a historic national effort that will use the power of artificial intelligence (AI) to accelerate discovery science, strengthen national security, and drive energy innovation.
December 18, 2025
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WASHINGTON—The U.S. Department of Energy (DOE) announced agreements with 24 organizations interested in collaborating to advance the Genesis Mission, a historic national effort that will use the power of artificial intelligence (AI) to accelerate discovery science, strengthen national security, and drive energy innovation. The announcement builds on President Trump’s Executive Order Removing Barriers to American Leadership In Artificial Intelligence and advances his America’s AI Action Plan released earlier this year—a directive to remove barriers to innovation, reduce dependence on foreign adversaries, and unleash the full strength of America’s scientific enterprise.
Today's White House meeting between industry participants, U.S. Secretary of Energy Chris Wright, U.S. Department of Energy Under Secretary for Science and Genesis Mission Director, Dr. Darío Gil, and Director of the White House Office of Science and Technology Policy Michael Kratsios helped launch public-private innovation partnerships in AI technologies to secure a scalable national infrastructure to push the boundaries of science at unprecedented speed and ensure the benefits of AI flow to the entire nation.
“Today’s announcement of 24 new research partnerships is only the beginning, as we deliver on President Trump’s mandate to bring the entire scientific community, including companies, universities, non-profits, and Federal agencies, into the Genesis Mission,” said Assistant to the President and OSTP Director Michael Kratsios. “Harnessing cutting-edge AI for science will dramatically increase the productivity of American scientists and researchers. The Genesis Mission will help America’s scientists automate experiment design, accelerate simulations, and generate predictive models that will lead to breakthroughs in energy, manufacturing, drug discovery, and beyond.”
“Thanks to President Trump’s leadership, the Genesis Mission will be transformative for our country, uniting industry, academia, and our National Labs to deliver powerful and impactful scientific discovery and innovation,” said DOE Under Secretary for Science and Genesis Mission Director, Dr. Darío Gil. “These agreements help advance President Trump’s Executive Order to build the national AI platform for scientific discovery and uplift the entire U.S. R&D ecosystem.”
The organizations that have signed memorandums of understanding (MOUs) as of today have either expressed interest to DOE in response to an RFI or have active projects with DOE and the National Laboratories for activities related to the Genesis Mission, and any products produced for the Genesis Mission will be architecture-agnostic. The organizations include:
- Accenture
- AMD
- Anthropic
- Armada
- Amazon Web Services
- Cerebras
- CoreWeave
- Dell
- DrivenData
- Groq
- Hewlett Packard Enterprise
- IBM
- Intel
- Microsoft
- NVIDIA
- OpenAI
- Oracle
- Periodic Labs
- Palantir
- Project Prometheus
- Radical AI
- xAI
- XPRIZE
DOE looks forward to future convenings with private industry collaborators, academia, and philanthropy to expand the number of qualified collaborators. The Department continues to welcome submissions to its open RFIs. The “Partnerships for Transformational Artificial Intelligence Models” RFI is open until Jan. 14, 2026. The “Transformational AI Capabilities for National Security” RFI is open until Jan. 23, 2026.
For the latest information on the Genesis Mission, visit www.genesis.energy.gov. For interest in partnerships please email genesismission-partnerships@hq.doe.gov.
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