DOE AI Use Case Inventory

The 2025 Department of Energy (DOE) Artificial Intelligence (AI) Use Case Inventory complies with the Office of Management and Budget Memorandum M-25-21. To explore DOE’s AI Use Case Inventory, please download our full spreadsheet here. To view the Consolidated Use Case Inventory containing estimated license counts across DOE-wide use-case categories, download the spreadsheet here.

Please find additional information on how DOE is developing tools, models, and partnerships to build AI foundation models for science, energy, and security here and at The Genesis Mission.

For questions, please reach out to AIGovernance@hq.doe.gov.