The Portsmouth Site, located in Piketon, Ohio, consisted of four main areas historically totaling more than 3,700 acres: the former gaseous diffusion plant, centrifuge facilities, depleted uranium hexafluoride conversion (DUF6) facility and On-Site Waste Disposal Facility (OSWDF). The largest of the three areas is the former gaseous diffusion plant, which consists of three main process buildings (X-333, X-330 and X-326) which housed the gaseous diffusion process equipment, as well as hundreds of supporting facilities. A seven-mile perimeter road contains the process buildings and over 400 structures and facilities.
The OSWDF is located northeast outside of the perimeter road and has a 300-acre footprint. More than 2,200 workers are employed at the site making it one of the largest employment drivers in the region. Currently, at the site, workers are continuing deactivation of the X-330 Process Building and are close to complete with deactivation at the X-333 Process Building.
Portsmouth News
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As the U.S. Department of Energy Office of Environmental Management works to enable American energy and security, innovative approaches and strong partnerships at the Portsmouth and Paducah sites drive efforts to transform liabilities into assets to help unleash nuclear power.September 30, 2025 -
As the U.S. Department of Energy Office of Environmental Management addresses the legacy of the past, it has incredible opportunities to be part of what’s been dubbed Manhattan Project 2.0, a strong vision for the future focused on winning the global artificial intelligence race and ushering in a nuclear renaissance to fuel it, acting EM Assistant Secretary Joel Bradburne said in the keynote address at the 2025 National Cleanup Workshop.September 24, 2025 -
U.S. Department of Energy officials and Paducah, Kentucky, community members take part in a meeting of the annual Paducah Chamber of Commerce Fly-In. September 23, 2025September 23, 2025 -
Career longevity has come into focus recently at the Portsmouth Site, where 17 of the more than 2,000 contractor workers there have marked over 50 years of service, with one employee at 56 years. September 16, 2025.September 16, 2025