The Portsmouth Site, located in Piketon, Ohio, consisted of four main areas historically totaling more than 3,700 acres: the former gaseous diffusion plant, centrifuge facilities, depleted uranium hexafluoride conversion (DUF6) facility and On-Site Waste Disposal Facility (OSWDF). The largest of the three areas is the former gaseous diffusion plant, which consists of three main process buildings (X-333, X-330 and X-326) which housed the gaseous diffusion process equipment, as well as hundreds of supporting facilities. A seven-mile perimeter road contains the process buildings and over 400 structures and facilities.
The OSWDF is located northeast outside of the perimeter road and has a 300-acre footprint, including support facilities. More than 2,200 workers are employed at the site making it one of the largest employment drivers in the region. Currently, at the site, workers are continuing deactivation of the X-330 Process Building and are close to complete with deactivation at the X-333 Process Building.
PortsDemo - Environmental Monitoring
The safety of our workers, our community and the environment is DOE’s top priority. The Department has a robust environmental monitoring program that meets or exceeds state and national regulatory standards.
Portsmouth News
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Sustainable purchasing of electronics helps reduce waste and conserve natural resources, lowering the impact of technology. August 11, 2026August 11, 2026 -
Security forces at the U.S. Department of Energy’s Portsmouth and Paducah sites are streamlining programs and services to strengthen protection of personnel, property and information, enabling more focus on completing cleanup and supporting future use opportunities at the sites. August 4, 2026August 4, 2026 -
Bringing together third grade students, high school mentors and interactive learning stations proved successful to introduce students to a wide range of career paths at the U.S. Department of Energy’s Portsmouth Site. July 14, 2026July 14, 2026 -
Heavy equipment and engineered design plans are not the only aspects of facility demolition at the U.S. Department of Energy’s Portsmouth Site. June 30, 2026June 30, 2026