Integrated process for commercial production of farnesene, a versatile platform chemical, from domestic lignocellulosic feedstock Award Number: DE-EE0007729 CX(s) Applied: A9, B3.6 Bioenergy Technologies Office Date: 9/8/2016 Location(s): CA O...
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September 16, 2016Integrated process for commercial production of farnesene, a versatile platform chemical, from domestic lignocellulosic feedstock
Award Number: DE-EE0007729
CX(s) Applied: A9, B3.6
Bioenergy Technologies Office
Date: 9/8/2016
Location(s): CA
Office(s): Golden Field Office
The U.S. Department of Energy (DOE) is proposing to provide federal funding to Amyris, Inc. to develop a manufacturing-ready, farnesene-fermentation process using cellulosic sugars that achieve cost parity with Amyris’ 1st generation sugar- manufacturing process using cane syrup.
Activities associated with the proposed project would include preliminary validation of current capabilities (Task A); cellulosic sugar production, concentration, and purification (Tasks B, J, K, Q, R); strain engineering (Tasks C, D, L, M, S) ; analysis of engineering products (Tasks E, F, N, U, V); selection and assessment of potential feedstock sites (Tasks G and H); integration optimization (Task I); design and installation of a simulated moving bed chromatography (SMB) unit (Task O); validation of project progress (Task P); and process development (Task T). These activities would take place at pre-existing, purpose-built facilities as follows:
• Amyris, Inc.—Research & Development (R&D) Lab in Emeryville, CA
Enzyme identification, Strain engineering, Analytical method development, Fermentation at up to 2 L scale, and Product analysis.
• Renmatix—R&D Lab, Headquarters, Pilot Plant in King of Prussia, PA
Bench-scale R&D, Analytical work, Pilot plant runs, Accounting, Legal, Administrative work, and Project management
• Renmatix—Feedstock Processing Facility in Rome, NY
Pretreatment and hemicellulose hydrolysis of pine wood chips
• Renmatix—Demonstration-scale plant in Kennesaw, GA
Supercritical water hydrolysis of biomass solids obtained from the Rome facility, refining of cellulosic sugars
• Total Marketing Services—Business Offices in Paris, France
Engineering studies, Techno-economic analysis, and Life-cycle analysis