A National Mission to Accelerate Science Through Artificial Intelligence
Genesis Mission is a national initiative to build the world's most powerful scientific platform to accelerate discovery science, strengthen national security, and drive energy innovation.
Goal
Genesis Mission will develop an integrated platform that connects the world's best supercomputers, experimental facilities, AI systems, and unique datasets across every major scientific domain to double the productivity and impact of American research and innovation within a decade.
Collaborators
Energy
Fusion you can plug into
Harnessing the power of the stars to deliver abundant, affordable energy. Through real-time collaboration between scientists, supercomputers, and AI systems, researchers can design, test, and stabilize fusion reactors far faster than before, accelerating the realization of sustainable fusion power.
Advanced nuclear, faster and safer
Creating a new generation of more efficient reactor designs, including new modular reactors, that provide reliable, around-the-clock energy. Engineers and AI tools work together to optimize reactor design, materials, licensing, and operations, shortening development timelines while strengthening safety and performance.
An intelligent, resilient grid
Building a power network that grows as fast as the technologies it fuels. By combining human expertise in energy planning with AI-enabled forecasting and simulation, teams can modernize the nation's grid, improving reliability and accelerating deployment of new infrastructure.
Discovery Science
Seeing molecules in action
Revealing chemical and biological processes as they unfold in real time. AI will work with ultrafast experiments to observe molecular dynamics and uncover insights that accelerate breakthroughs in materials and medicine.
Understanding the universe, from quarks to cosmos
Connecting the smallest particles to the largest structures. Physicists, guided by AI tools that reason across astronomical and particle-physics data, work together to test new theories about dark matter, dark energy, and the laws of nature.
Discovering new quantum algorithms
Unlocking the next frontier of computation. AI serves as a reasoning partner for researchers, generating and verifying new classes of quantum algorithms while scientists interpret and validate the results, bringing practical quantum computing closer to reality.
National Security
Securing critical materials
Reducing dependence on foreign supply chains. Materials scientists and AI systems co-design substitutes, responsibly utilize Earth's resources, and recover rare elements from waste, building a stable, self-reliant foundation for the nation's future industries.
Accelerating advanced manufacturing
Turning design into production at the speed of need. Engineers and AI-driven digital twins share a continuous feedback loop between design, sensors, and fabrication, cutting qualification time and boosting efficiencies.
Discovering mission-ready materials
Delivering alloys, polymers, and composites vital to defense and industry. Human insight and AI-guided discovery converge to fuse simulation, literature mining, and autonomous labs, pointing toward a future where years of materials research could unfold in a fraction of the time.
Essential Information and Guidance
A national initiative led by the Department of Energy and its 17 National Laboratories to build the world’s most powerful scientific platform to accelerate discovery, strengthen national security, and drive energy innovation.
We are amid a revolution in computing, driven by artificial intelligence and quantum information technologies, that will transform how science is done. Genesis Mission has the goal of doubling the productivity and impact of U.S. research and development by pairing scientists with intelligent systems that reason, simulate, and experiment at extraordinary speed.
Genesis Mission will create a national discovery platform that unites the world’s most powerful supercomputers, AI systems, and emerging quantum technologies with the nation’s most advanced scientific instruments. Together, they form an integrated infrastructure for scientific exploration—an intelligent network capable of sensing, simulating, and understanding nature at every scale.
By connecting these systems, Genesis Mission will transform how science is done. It will generate a new class of high-fidelity data to train advanced AI models, empower researchers to solve the hardest scientific challenges, and accelerate discovery from years to months. In doing so, it will serve as both a national accelerator for innovation and a proving ground for the next generation of AI and quantum and robotics technologies.From fusion energy and new materials to quantum computing and life-saving medicines, Genesis Mission expands what’s possible in energy, discovery science, and national security.
Unlike commercial models trained on the open internet, Genesis Mission draws from the government’s secure, multi-domain scientific data, decades of experiments unavailable anywhere else.
No. Genesis Mission enables them. It’s AI for discovery, not automation, helping researchers explore and understand the universe faster.
The Department of Energy, in partnership with the White House Office of Science and Technology Policy.
Genesis Mission brings together the Department of Energy’s 17 National Laboratories with America’s leading universities and industry, including pioneers in artificial intelligence, computing, materials, and energy, to build the most powerful scientific platform ever to solve national challenges.
The initial collaborators listed below. Together, they represent the strength of the U.S. innovation ecosystem, uniting public and private sectors to accelerate discovery and maintain America’s scientific and technological leadership.
Genesis Mission is a movement to transform how science is done. DOE will open parts of Genesis Mission platform to qualified researchers, innovators, and companies, ensuring the benefits of this national effort are shared across the American scientific ecosystem. Learn more.
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