The Fuel Cell Technologies Office organized an H2@Scale Session on November 7, 2017, at the Fuel Cell Seminar in Long Beach, California to (1) provide an overview of current and upcoming early-stage R&D activities within H2@Scale, including selections from the 2017 H2@Scale CRADA Call; (2) identify opportunities to align hydrogen technologies with evolution in power generation, transmission, and transportation sectors; and (3) assess hydrogen infrastructure needs to align and enable growth of diverse industries.