The Mission of the Office of Technology Transitions is to expand the public impact of the department's research and development (R&D) portfolio to advance the economic, energy and national security interests of the nation. OTT is the front door to DOE's products, facilities and expertise. The office integrates "market pull" into its planning to ensure the greatest return on investment from DOE's R&D activities to the taxpayer.

Hosting one of the world's largest science research enterprises, the U.S. Department of Energy (DOE) helps power and secure America's future through technological advancement and strategic support. DOE's R&D capabilities, and the innovations they enable, help maintain the United States' role as the global leader in science and technology. In particular, technology transfer supports the maturation and deployment of DOE-powered innovation, providing ongoing economic, security and environmental benefits for all Americans.

In 2015, the Secretary of Energy authorized the formation of the Office of Technology Transitions (OTT) to be responsible for developing and overseeing delivery of DOE's strategic vision and goals for technology commercialization and engagement with the business and industrial sectors across the United States. OTT's statutory authority is derived from the Bayh-Dole Act of 1980, Stevenson-Wydler Technology Innovation Act of 1980, Energy Policy Act of 2005, and Energy Act of 2020. OTT's mission is to expand the commercial impact and public benefit of DOE's research, development, demonstration, and deployment (RDD&D) portfolio to advance the economic, energy, and national security interests of the nation.