The Portsmouth Site, located in Piketon, Ohio, consisted of four main areas historically totaling more than 3,700 acres: the former gaseous diffusion plant, centrifuge facilities, depleted uranium hexafluoride conversion (DUF6) facility and On-Site Waste Disposal Facility (OSWDF). The largest of the three areas is the former gaseous diffusion plant, which consists of three main process buildings (X-333, X-330 and X-326) which housed the gaseous diffusion process equipment, as well as hundreds of supporting facilities. A seven-mile perimeter road contains the process buildings and over 400 structures and facilities.
The OSWDF is located northeast outside of the perimeter road and has a 300-acre footprint, including support facilities. More than 2,200 workers are employed at the site making it one of the largest employment drivers in the region. Currently, at the site, workers are continuing deactivation of the X-330 Process Building and are close to complete with deactivation at the X-333 Process Building.
PortsDemo - Environmental Monitoring
The safety of our workers, our community and the environment is DOE’s top priority. The Department has a robust environmental monitoring program that meets or exceeds state and national regulatory standards.
Portsmouth News
-
Two educators in communities near the U.S. Department of Energy’s Portsmouth, Ohio, and Paducah, Kentucky, locations are maximizing resources to help cultivate the next generation of talent to advance the nation’s energy sector and future redevelopment at the DOE sites. May 19, 2026May 19, 2026 -
Demolition crews recently unleashed equipment, dubbed locally as the “Empress,” to begin tearing through the steel framework of the X-333 Process Building at the U.S. Department of Energy’s Portsmouth Site. May 5, 2026May 5, 2026 -
Decades of uranium enrichment operations at two former gaseous diffusion plants yielded thousands of cylinders of depleted uranium hexafluoride, or DUF6, that accumulated in storage yards. April 21, 2026April 21, 2026 -
SB Energy, a SoftBank Group company, recently announced a unique public-private partnership to construct the world’s largest artificial intelligence data center on leased land at the U.S. Department of Energy’s Portsmouth Site. April 7, 2026April 7, 2026