This report addresses the Scope of Work (SOW) for Task Order 16, “Generic Design Alternatives for Dry Storage of Used Nuclear Fuel,” issued in March 2014 by the Department of Energy’s (DOE’s) Office of Nuclear Energy (DOE-NE). It develops and documents a suite of generic design alternatives for the receipt, processing and storage of the SNF and greater than Class C (GTCC) waste for the initial Pilot ISF, assuming the SNF and GTCC is derived from shutdown reactors. This report also seeks to provide DOE with maximum flexibility for additional capabilities to be developed and executed in a modular fashion such that the option for an Expanded Pilot ISF could be achieved in an orderly and cost effective manner.