Ultra-low temperature laboratory freezers (ULTs) are some of the most energy-intensive pieces of equipment in a scientific research laboratory, yet there are several barriers to user acceptance and adoption of high-efficiency ULTs. One significant barrier is a relative lack of information on ULT efficiency to help purchasers make informed decisions with respect to efficient products. Through the U.S. Department of Energy (DOE) Better Buildings Alliance (BBA) program, we conducted a field demonstration to show the energy savings that can be achieved in the field with high-efficiency equipment. The results of the demonstration provide more information to purchasers for whom energy efficiency is a consideration. The findings of the demonstration are also intended to support efforts by the BBA and others to increase the market penetration of high-efficiency ULTs.